hrp0097p1-292 | GH and IGFs | ESPE2023

Clinical predictors of good/poor response to growth hormone treatment (GHT) in children with idiopathic short stature (ISS)

Dauber Andrew , Phillip Moshe , Ferran Jean-Marc , Kelepouris Nicky , Nedjatian Navid , Helene Olsen Anne , Jorge Alexander

Children with ISS vary in their response to GHT. We conducted a post hoc analysis to identify clinical characteristics associated with very good or poor response during year 1 of GHT in a subset of 1550 GH naïve children with ISS from NordiNet® IOS (NCT00960128) and the ANSWER Program (NCT01009905). We included patients aged 3–11 years (males) or 3–10 years (females) at treatment start, prepubertal throughout year 1 of treatment, with height SDS...